Description

🩺 What It’s For

• Primary use: Management of osteoarthritis—particularly in knees and hips. It helps reduce joint pain, inflammation, and stiffness while supporting cartilage repair over time (PharmEasy, 1mg).
• The ingredients and dose per tablet typically include:
  • Diacerein 50 mg – an anti-inflammatory that slows cartilage degradation (MedPlusMart).
  • Glucosamine Sulfate 446–750 mg – supports cartilage structure and function (1mg).
  • MSM 250 mg – offers sulfur for joint tissue repair and has antioxidant/anti-inflammatory effects (MedPlusMart).

✅ How It Works

• Diacerein inhibits inflammatory cytokines (like IL‑1β), reducing cartilage breakdown (TrueMeds).
• Glucosamine promotes synthesis of cartilage components, improving joint lubrication (WebMD).
• MSM supplies sulfur aid tissue repair and complements anti-inflammatory benefits (1mg).
• Time to relief: Often takes several weeks of consistent use to experience noticeable effects (PlatinumRx).

⚠️ Common Side Effects

• Digestive issues: nausea, vomiting, diarrhea, constipation, indigestion, heartburn, stomach ache (PharmEasy, MedPlusMart, 1mg).
• Urine discoloration (yellowish) — typically harmless (1mg).
• Headache and mild skin rash may occur (Medcart).

⚠️ Less Common / Serious Risks

• Liver enzyme increase — monitor if you have pre-existing liver conditions (Medcart, 1mg, TrueMeds).
• Allergic skin reactions — though rare, can occur (Medcart, MedPlusMart).
• Asthma, glaucoma, diabetes, or blood-thinning meds may interact with glucosamine/MSM (Medcart).

⚠️ Who Should Be Cautious

• Liver or kidney disease: may be unsafe or require close monitoring (crinovahealthcare.com).
• Pregnant or breastfeeding: insufficient safety data—consult your doctor (PlatinumRx).
• Shellfish allergy: glucosamine is often derived from shellfish—advice needed if allergic (TrueMeds).
• Other medications: possible interactions with anticoagulants, diabetes drugs, chemotherapy, etc. (TrueMeds).
• Alcohol: high intake may further stress the liver—use caution (Medcart).

💡 How to Use

• Take with food to minimize stomach discomfort (PharmEasy).
• Typical dose is as prescribed—usually 1 tablet once or twice daily (Medcart).
• Missed dose: take when remembered, unless it’s near the next dose. Do not double dose (1mg, crinovahealthcare.com).
• Treatment duration: often recommended for several weeks or months—evaluate efficacy after a few months (1mg, PlatinumRx, PharmEasy).

✅ Summary Table