Description

✅ What is it used for?

Disfit Tablet contains disulfiram, which helps treat alcohol dependence. It works by blocking the enzyme aldehyde dehydrogenase, causing unpleasant reactions if alcohol is consumed—acting as a deterrent to drinking (NetForHealth).

Primary use:

• Supportive therapy to maintain abstinence in alcohol use disorder, when used alongside counseling and behavior modification programs (Drugs.com).

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⚠️ Side Effects

1. Disulfiram–Alcohol Reaction

Occurs if alcohol is consumed while taking Disfit:

• Flushing, throbbing headache, nausea, vomiting, sweating, dizziness, rapid heartbeat, chest pain, low blood pressure, weakness.
• Symptoms usually last 30 mins to several hours; can rarely cause severe outcomes like shock or even death (Mayo Clinic).

2. Common (usually mild)

• Headache, fatigue, drowsiness, dizziness, metallic or garlic-like aftertaste (1mg).
• Digestive issues: nausea, upset stomach (Mayo Clinic).
• Flushing, sweating .

3. Sexual and Skin Effects

• Sexual dysfunction (impotence, decreased libido) (GoodRx).
• Skin issues: acne, rash, itching (GoodRx).

4. Serious (rare but critical)

• Liver toxicity: monitor for jaundice, dark urine, abdominal pain; liver function tests recommended before and during treatment (NetForHealth).
• Neurological issues: peripheral neuropathy, numbness, tingling (DawaiWala).
• Psychiatric effects: psychosis, hallucinations, confusion—especially in those with mental health history or who take interacting drugs .

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⚕️ Important Precautions

• No alcohol allowed—includes beverages, cough syrups, mouthwash, vinegars, perfumes, aftershave, and sauces (Farmako).
• Avoid if recently taken certain drugs (e.g., metronidazole) or alcohol in last 12 hrs (Drugs.com).
• Caution or avoid if you have: liver disease, psychosis, heart disease, diabetes, seizures, kidney problems .
• Use during pregnancy or breastfeeding only if clearly needed, per doctor’s advice .
• May cause drowsiness/dizziness—avoid driving until you know how it affects you (Farmako).

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💡 Usage Tips

• Take once daily at the same time, with or without food, as prescribed (1mg).
• Do not skip doses abruptly—sticky continuity is important .
• If you miss a dose, skip it and continue normally; don’t double up .
• Combination with counseling significantly boosts success (Farmako).

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📝 Summary Table

Aspect	Details
Mechanism	Blocks aldehyde dehydrogenase → acetaldehyde build-up
Goal	Discourage alcohol intake
Common Reactions	Headache, fatigue, metallic taste
Severe Risks	Liver injury, nerve damage, psychiatric symptoms
Monitoring	Liver tests, watch for neuro/psych signs
Abstinence	Must avoid all alcohol forms

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📌 Final Note

Disfit 250 is a prescription drug—use strictly under medical supervision. Its effectiveness hinges on consistency, regular medical check-ups, and supportive therapy, with strict avoidance of any alcohol.