Description

🧾 What is it used for?

ITRONAZOLE-100 Tablet by Austro Lab contains Itraconazole 100 mg, which is a broad-spectrum antifungal medicine. It works by stopping the growth of fungi by interfering with their cell membranes.

It is used to treat fungal infections such as:

• Skin infections: Tinea corporis (ringworm), Tinea cruris (jock itch), Tinea pedis (athlete’s foot)

• Nail infections (onychomycosis)

• Oral and esophageal candidiasis (mouth/throat fungal infections)

• Vaginal candidiasis

• Systemic fungal infections such as histoplasmosis, aspergillosis (in serious cases)

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⚠️ Common Side Effects

Most users tolerate it well, but some may experience:

• Nausea or vomiting

• Stomach pain or discomfort

• Diarrhea or constipation

• Headache

• Dizziness or tiredness

• Skin rash or itching

• Taste disturbances

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🚨 Serious Warnings & Precautions

• Liver toxicity: Can cause serious liver damage; monitor liver function if used long-term or in patients with pre-existing liver issues

• Heart issues: May worsen congestive heart failure (CHF); avoid in such patients unless absolutely necessary

• Drug interactions: Itraconazole is known for multiple serious interactions (especially with heart, cholesterol, and psychiatric medications)

• Hearing loss: Rarely, reversible or irreversible hearing loss has been reported

• Neuropathy: Tingling, numbness, or nerve pain may occur with prolonged use

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🔄 Drug & Food Interactions

• Antacids/acid reducers (e.g., omeprazole, ranitidine): Reduce absorption of itraconazole—avoid using these within 2 hours

• Statins (cholesterol medicines): Risk of muscle damage—avoid unless doctor approves

• Heart rhythm drugs (e.g., quinidine, dofetilide): Dangerous QT prolongation risk—contraindicated

• Rifampin or phenytoin: Reduce the effect of itraconazole

• Alcohol: May increase risk of liver damage

• Grapefruit juice: Can increase blood levels of the drug—avoid

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👥 Cautionary Groups

• Pregnancy: Not recommended unless life-threatening fungal infection is present

• Breastfeeding: Avoid—may pass into breast milk

• Children: Use only if clearly needed and prescribed

• Elderly: Increased risk of side effects—monitor closely

• Patients with liver, kidney, or heart disease: Use with strict medical supervision

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✅ Tips for Safe Use

1. Take after a full meal for better absorption

2. Do not crush or chew the tablet—swallow whole

3. Avoid antacids or acid-reducing agents 2 hours before/after

4. Monitor liver function tests if taking long-term

5. Report unusual symptoms: yellowing eyes/skin, dark urine, persistent fatigue

6. Avoid self-medication or stopping abruptly—complete the full course

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📌 When to Consult a Doctor Immediately

• Yellowing of skin or eyes (liver dysfunction)

• Persistent nausea, vomiting, or abdominal pain

• Irregular heartbeat, chest pain, or shortness of breath

• Hearing problems or ringing in ears

• Severe skin reactions (rash, peeling, blisters)

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🧠 Summary Table