Description
🩺 Common Uses
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Preventing/treating hypocalcemia (low blood calcium), especially when dietary intake is insufficient WebMDCleveland Clinic.
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Bone disorders including osteoporosis, osteomalacia, osteoarthritis, rickets Healthline+5MedlinePlus+5Kaiser Permanente+5.
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Adjunctive therapy in chronic kidney disease or dialysis patients to support mineral balance 24buyonline.
⚠️ Common Side Effects
Typically mild and transient, may include:
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Digestive issues: constipation, upset stomach, nausea, diarrhea, loss of appetite Kaiser Permanente.
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Gastrointestinal discomfort (e.g. vomiting, stomach pain, constipation) especially with higher doses Cleveland Clinic+2Healthline+2Kaiser Permanente+2.
🚨 Less Common but Serious Side Effects
Rare cases of hypercalcemia (excess calcium in the blood) can occur, often due to excessive vitamin D intake or underlying health conditions:
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Symptoms include: increased thirst/urination, fatigue, muscle weakness, confusion, vomiting, constipation, kidney stones or injury, abnormal heart rhythms WebMD+3Healthline+324buyonline+3.
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Allergic reactions: rash, itching, hives, swelling of face/lips/throat, breathing difficulties—seek immediate medical attention if these occur Cleveland Clinic.
📝 Precautions & Interactions
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Use with caution or medical supervision if you have:
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Kidney or liver disease
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History of kidney stones or hyperparathyroidism
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High baseline calcium levels Cleveland Clinic.
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Potential drug interactions:
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Antibiotics (e.g., ciprofloxacin, tetracyclines)
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Heart medications like digoxin
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Diuretics, iron supplements, antifungals, thyroid meds, sucralfate and others—these may impair absorption or increase levels Cleveland Clinic+1Kaiser Permanente+1.
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✅ Usage Tips
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Take as directed by your healthcare provider, typically with meals and a full glass of water to aid absorption Cleveland Clinic+1Drugs.com+1.
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Avoid exceeding the recommended dose—too much vitamin D (especially >10,000 IU/day) can dramatically increase calcium absorption and risk toxicity Cleveland Clinic+3Healthline+3MedlinePlus+3.
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Monitor periodically with blood tests if you’re on long-term or high-dose treatment, especially for calcium and vitamin D levels.
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Separate timing when taking other medications like iron, thyroid medicines, or antibiotics, to prevent interaction Cleveland ClinicDrugs.com.
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