Description
✅ Uses
Cefixime is a third‑generation cephalosporin antibiotic. Cefixal 200 DT is prescribed for a variety of bacterial infections, including:
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Ear, nose, and throat infections (sinusitis, pharyngitis, tonsillitis, otitis media)
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Upper and lower respiratory infections (bronchitis, pneumonia)
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Urinary tract infections (such as cystitis and kidney infections)
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Uncomplicated gonorrhea (urethral/cervical infections)
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In some regions, also used for typhoid fever and shigella/salmonella diarrheas MedBroadcast+15Apollo Pharmacy+15Drugs.com+15Pharmacistsite
⚠️ How It Works
Cefixime works by inhibiting bacterial cell wall synthesis, effectively killing the bacteria and stopping infection growth Reddit+2Drugs.com+2Wikipedia+2.
🩺 Dosage & Administration
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Usual adult dose: 200–400 mg once or twice daily, depending on the infection and doctor’s advice HealMotive.
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Dispersible form: dissolve in water and swallow; do not crush or chew Reddit+15Apollo Pharmacy+15HealMotive+15.
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Always complete the full course—even if symptoms improve—to avoid resistance and incomplete treatment Illness Hacker+15MedlinePlus+15HealMotive+15.
🔍 Common Side Effects
Usually mild and often resolve during therapy:
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Gastrointestinal: diarrhea, loose stools, nausea, vomiting, abdominal pain, indigestion, gas
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Other: headache, dizziness, loss of appetite Yashoda HospitalsCleveland Clinic
🚨 Serious Side Effects (Less Frequent)
Contact a doctor immediately if any of the following occur:
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Severe allergic reactions: rash, hives, swelling (face, throat, tongue, lips), difficulty breathing or swallowing, wheezing Apollo Pharmacy+13WebMD+13Saint Luke’s Health System Kansas City+13Yashoda Hospitals+2Saint Luke’s Health System Kansas City+2MedlinePlus+2
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Persistent or watery/bloody diarrhea—could indicate Clostridioides difficile infection. This can appear during therapy or weeks to months after stopping Wikipedia+3WebMD+3Cleveland Clinic+3
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Signs of liver or kidney issues: jaundice (yellowing skin/eyes), dark urine, change in urination, fatigue
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Blood disorders: unusual bleeding/bruising, anemia, low white blood cell or platelet counts
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CNS effects (rare): seizures or confusion—especially if there’s reduced renal function WebMDPharmacistsiteMedBroadcast
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Severe skin reactions, including blistering, peeling, or Stevens–Johnson syndrome Cleveland Clinic
📌 Precautions & Contraindications
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Allergy alert: Not advised for individuals allergic to cefixime or other cephalosporins (and possibly penicillins due to cross-reactivity) Apollo Pharmacy+5Drugs.com+5Pharmacistsite+5.
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Kidney or liver disease: May require dose adjustments and close monitoring Medicover Hospitals+1MedlinePlus+1.
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Seizure disorders: Use caution due to potential risk of seizures when drug levels are elevated MedlinePlus+14MedBroadcast+14Illness Hacker+14.
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PKU (phenylketonuria): Some chewable forms contain aspartame (a source of phenylalanine) which may be problematic Drugs.com+2MedlinePlus+2Medicover Hospitals+2.
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Pregnancy and breastfeeding: Use only if clearly needed and under medical supervision; appears relatively safe but consult your doctor Apollo Pharmacy+1Pharmacistsite+1.
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Contraceptive caution: Cefixime may reduce effectiveness of hormonal contraceptives—use additional birth control methods as advised Reddit+15MedlinePlus+15Pharmacistsite+15.
💊 Drug Interactions
Potential interactions include:
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Vaccines: BCG, typhoid, cholera may be less effective if taken concurrently
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Anticoagulants: e.g., warfarin (may increase bleeding risk)
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Anticonvulsants: carbamazepine (levels may be affected)
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Caution with aspirin-like drugs and others (e.g., certain antibiotics, supplements) Cleveland Clinic
🌿 Real‑World Experiences (User Reports)
Reddit users commonly describe:
“Generally very well tolerated…but I feel nauseous, tired and got headaches”—especially when already ill Reddit+1Reddit+1Reddit
“Slight diarrhea… took probiotic to stabilize” during sinusitis therapy Reddit
Some mention dizziness and mild discomfort early in therapy, which often improves after a few days RedditReddit.
📝 Summary Table
Aspect | Details |
---|---|
Indications | RTIs, UTIs, ENT infections, gonorrhea, typhoid, shigellosis |
Form | 200 mg dispersible tablet (DT) |
Dose | 200–400 mg once or twice daily, as prescribed |
Common AEs | GI upset, headache, dizziness |
Serious AEs | Allergic reactions, C. difficile diarrhea, liver/kidney issues, seizures, blood changes |
Contraindications | Known allergy to cephalosporins or penicillins |
Precautions | Pregnancy, lactation, renal/liver dysfunction, seizure disorders, PKU |
Interactions | Vaccines, warfarin, carbamazepine, aspirin, etc. |
Reviews
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