Description

🩺 Composition & Primary Use

• Drotaverine hydrochloride (80 mg) – a potent antispasmodic that relaxes smooth muscles (such as in gut, cervix, urinary system) by inhibiting PDE‑4 and increasing cAMP levels, easing spasm-related pain International Drug Mart+15Practo+15Farmako+15Yashoda Hospitals+5Caresupp.in+5Wikipedia+5.

• Often paired with Mefenamic acid (250 mg) – a non‑steroidal anti‑inflammatory drug providing additional pain relief and reducing inflammation in abdominal cramps (when sold as Drotiost‑MF) PractoONUS Health Care Private LimitedCaresupp.inPracto.

Main Uses:

• Relieving abdominal and menstrual cramps, renal colic (kidney stone pain), biliary colic, IBS-related cramps, and smooth muscle spasms in gastrointestinal, urinary, or uterine systems PharmBaba+1Yashoda Hospitals+1.

💊 Dosage & Administration

• Adults: Typically 40–80 mg drotaverine (one tablet) taken three times a day, with or without food. If combined with mefenamic acid, taken after food to minimize GI upset novalabgynecare.com+15Medindia+15Caresupp.in+15.

• Children: Dosage based on age/weight; generally lower amounts (e.g., 20–40 mg tablets split accordingly) PharmBaba+2Yashoda Hospitals+2Practo+2.

• Swallow whole—do not crush or chew the tablet Farmako+2PharmBaba+2Apollo Hospitals+2.

⚠️ Common & Serious Side Effects

Common mild side effects:

• Nausea, vomiting

• Dry mouth

• Dizziness, headache

• Constipation or flushing

• Sleep disturbances (insomnia)

• Some may experience increased sweating or changes in heart rate International Drug Mart+15PharmBaba+15Practo+15novalabgynecare.com+1ONUS Health Care Private Limited+1.

Less common but serious possible reactions:

• Allergic dermatitis, facial swelling (lips, tongue, eyelids), breathing difficulty

• Drop in blood pressure (hypotension), tachycardia

• Rare instances of significant liver enzyme changes, anaemia, hypoesthesia or cardiac rhythm changes Practo+1novalabgynecare.com+1.

Overdose risks:

• Symptoms may include confusion, seizures, cardiac arrest, respiratory paralysis—seek urgent medical attention Wikipediabioniquepharma.com.

👩‍⚕️ Precautions & Interactions

• Contraindications: Known allergy to drotaverine, severe liver, kidney, or heart disorders, blood disorders like porphyria Apollo Hospitals+14PharmEasy+14Pace Hospital+14.

• Pregnancy & Breastfeeding: Use only under strict medical guidance; generally not recommended during pregnancy or lactation PharmBabaPractoONUS Health Care Private Limited.

• With Alcohol: Avoid alcohol—it can amplify dizziness, hypotension, and may increase side-effect risk PharmEasy+1Practo+1.

• Driving/Cognitive Tasks: Dizziness or drowsiness can occur; avoid driving or operating heavy machinery until you know how the medication affects you Practo+1Caresupp.in+1.

• Other medications: Inform your doctor if taking other medications (especially painkillers, herbal supplements) to avoid interactions and additive effects PractoONUS Health Care Private Limited.

• Liver/Kidney Monitoring: Use cautiously in existing liver or kidney disease; doctor may recommend periodic function tests Medindia+1ONUS Health Care Private Limited+1.

✅ Quick Overview